This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACTR1B-20-RE | 20 (40 μL) | 200 μL |  |
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| ACTR1B-20-OR | 20 (40 μL) | 200 μL |  |
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| ACTR1B-20-GO | 20 (40 μL) | 200 μL |  |
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| ACTR1B-20-GR | 20 (40 μL) | 200 μL |  |
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| ACTR1B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008]
Gene Symbol : ACTR1B
Gene Name : ARP1 actin related protein 1 homolog B
Chromosome : CHR 2: 976,640,97-976,559,38
Locus : 2q11.2
Alt. Genes : PLXNC1
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