This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACVR1B-20-RE | 20 (40 μL) | 200 μL |  |
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| ACVR1B-20-OR | 20 (40 μL) | 200 μL |  |
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| ACVR1B-20-GO | 20 (40 μL) | 200 μL |  |
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| ACVR1B-20-GR | 20 (40 μL) | 200 μL |  |
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| ACVR1B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
Gene Symbol : ACVR1B
Gene Name : Activin A receptor type 1B
Chromosome : CHR 12: 519,516,66-519,970,78
Locus : 12q13.13
Alt. Genes : LINC01587
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