ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACVR1C-20-RE | 20 (40 μL) | 200 μL |  |
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| ACVR1C-20-OR | 20 (40 μL) | 200 μL |  |
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| ACVR1C-20-GO | 20 (40 μL) | 200 μL |  |
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| ACVR1C-20-GR | 20 (40 μL) | 200 μL |  |
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| ACVR1C-20-AQ | 20 (40 μL) | 200 μL |  |
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ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
Gene Symbol : ACVR1C
Gene Name : Activin A receptor type 1C
Chromosome : CHR 2: 157,628,886-157,526,766
Locus : 2q24.1
Alt. Genes : RAD50
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