This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature sperm surface protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ADAM18-20-RE | 20 (40 μL) | 200 μL |  |
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| ADAM18-20-OR | 20 (40 μL) | 200 μL |  |
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| ADAM18-20-GO | 20 (40 μL) | 200 μL |  |
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| ADAM18-20-GR | 20 (40 μL) | 200 μL |  |
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| ADAM18-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature sperm surface protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Gene Symbol : ADAM18
Gene Name : ADAM metallopeptidase domain 18
Chromosome : CHR 8: 395,845,67-397,300,63
Locus : 8p11.22
Alt. Genes : STAG1
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