This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ADAMTS10-20-RE | 20 (40 μL) | 200 μL |  |
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| ADAMTS10-20-OR | 20 (40 μL) | 200 μL |  |
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| ADAMTS10-20-GO | 20 (40 μL) | 200 μL |  |
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| ADAMTS10-20-GR | 20 (40 μL) | 200 μL |  |
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| ADAMTS10-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]
Gene Symbol : ADAMTS10
Gene Name : ADAM metallopeptidase with thrombospondin type 1 motif 10
Chromosome : CHR 19: 861,073,4-858,023,9
Locus : 19p13.2
Alt. Genes : CLEC3A
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