This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ADAMTS13-20-RE | 20 (40 μL) | 200 μL |  |
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| ADAMTS13-20-OR | 20 (40 μL) | 200 μL |  |
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| ADAMTS13-20-GO | 20 (40 μL) | 200 μL |  |
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| ADAMTS13-20-GR | 20 (40 μL) | 200 μL |  |
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| ADAMTS13-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Symbol : ADAMTS13
Gene Name : ADAM metallopeptidase with thrombospondin type 1 motif 13
Chromosome : CHR 9: 133,414,338-133,459,402
Locus : 9q34.2
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