This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ADAMTS3-20-RE | 20 (40 μL) | 200 μL |  |
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| ADAMTS3-20-OR | 20 (40 μL) | 200 μL |  |
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| ADAMTS3-20-GO | 20 (40 μL) | 200 μL |  |
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| ADAMTS3-20-GR | 20 (40 μL) | 200 μL |  |
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| ADAMTS3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016]
Gene Symbol : ADAMTS3
Gene Name : ADAM metallopeptidase with thrombospondin type 1 motif 3
Chromosome : CHR 4: 725,687,98-722,809,68
Locus : 4q13.3
Alt. Genes : OPTN
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