This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. [provided by RefSeq, Mar 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ADAMTS6-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
ADAMTS6-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
ADAMTS6-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
ADAMTS6-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
ADAMTS6-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. [provided by RefSeq, Mar 2016]
Gene Symbol : ADAMTS6
Gene Name : ADAM metallopeptidase with thrombospondin type 1 motif 6
Chromosome : CHR 5: 654,820,13-651,487,35
Locus : 5q12.3
Alt. Genes : ENAM
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