The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease. [provided by RefSeq, Feb 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ADAMTS7-20-RE | 20 (40 μL) | 200 μL |  |
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| ADAMTS7-20-OR | 20 (40 μL) | 200 μL |  |
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| ADAMTS7-20-GO | 20 (40 μL) | 200 μL |  |
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| ADAMTS7-20-GR | 20 (40 μL) | 200 μL |  |
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| ADAMTS7-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease. [provided by RefSeq, Feb 2016]
Gene Symbol : ADAMTS7
Gene Name : ADAM metallopeptidase with thrombospondin type 1 motif 7
Chromosome : CHR 15: 788,114,63-787,592,02
Locus : 15q25.1
Alt. Genes : CELA3A
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