This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ADCY5-20-RE | 20 (40 μL) | 200 μL |  |
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| ADCY5-20-OR | 20 (40 μL) | 200 μL |  |
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| ADCY5-20-GO | 20 (40 μL) | 200 μL |  |
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| ADCY5-20-GR | 20 (40 μL) | 200 μL |  |
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| ADCY5-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Symbol : ADCY5
Gene Name : Adenylate cyclase 5
Chromosome : CHR 3: 123,448,631-123,282,295
Locus : 3q21.1
Alt. Genes : OPTN
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