This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ADGRE2-20-RE | 20 (40 μL) | 200 μL |  |
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| ADGRE2-20-OR | 20 (40 μL) | 200 μL |  |
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| ADGRE2-20-GO | 20 (40 μL) | 200 μL |  |
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| ADGRE2-20-GR | 20 (40 μL) | 200 μL |  |
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| ADGRE2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Gene Symbol : ADGRE2
Gene Name : Adhesion G protein-coupled receptor E2
Chromosome : CHR 19: 147,785,40-147,326,96
Locus : 19p13.12
Alt. Genes : COG5
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