This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ADGRG1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
ADGRG1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
ADGRG1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
ADGRG1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
ADGRG1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Gene Symbol : ADGRG1
Gene Name : Adhesion G protein-coupled receptor G1
Chromosome : CHR 16: 576,195,34-576,650,38
Locus : 16q21
Alt. Genes : CLEC3A
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