This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AFF3-20-RE | 20 (40 μL) | 200 μL |  |
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| AFF3-20-OR | 20 (40 μL) | 200 μL |  |
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| AFF3-20-GO | 20 (40 μL) | 200 μL |  |
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| AFF3-20-GR | 20 (40 μL) | 200 μL |  |
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| AFF3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : AFF3
Gene Name : AF4/FMR2 family member 3
Chromosome : CHR 2: 100,142,582-995,458,60
Locus : 2q11.2
Alt. Genes : RAD50
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