The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AKR7A2-20-RE | 20 (40 μL) | 200 μL |  |
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| AKR7A2-20-OR | 20 (40 μL) | 200 μL |  |
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| AKR7A2-20-GO | 20 (40 μL) | 200 μL |  |
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| AKR7A2-20-GR | 20 (40 μL) | 200 μL |  |
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| AKR7A2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Symbol : AKR7A2
Gene Name : Aldo-keto reductase family 7 member A2
Chromosome : CHR 1: 193,121,45-193,027,07
Locus : 1p36.13
Alt. Genes : SLC35B1
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