This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AKT2-20-RE | 20 (40 μL) | 200 μL |  |
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| AKT2-20-OR | 20 (40 μL) | 200 μL |  |
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| AKT2-20-GO | 20 (40 μL) | 200 μL |  |
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| AKT2-20-GR | 20 (40 μL) | 200 μL |  |
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| AKT2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]
Gene Symbol : AKT2
Gene Name : AKT serine/threonine kinase 2
Chromosome : CHR 19: 402,855,30-402,303,16
Locus : 19q13.2
Alt. Genes : TRIM28
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