This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. [provided by RefSeq, Jul 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALDH8A1-20-RE | 20 (40 μL) | 200 μL |  |
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| ALDH8A1-20-OR | 20 (40 μL) | 200 μL |  |
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| ALDH8A1-20-GO | 20 (40 μL) | 200 μL |  |
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| ALDH8A1-20-GR | 20 (40 μL) | 200 μL |  |
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| ALDH8A1-20-AQ | 20 (40 μL) | 200 μL |  |
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This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. [provided by RefSeq, Jul 2010]
Gene Symbol : ALDH8A1
Gene Name : Aldehyde dehydrogenase 8 family member A1
Chromosome : CHR 6: 134,950,121-134,917,389
Locus : 6q23.3
Alt. Genes : LRPPRC
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