The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALKBH3-20-RE | 20 (40 μL) | 200 μL |  |
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| ALKBH3-20-OR | 20 (40 μL) | 200 μL |  |
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| ALKBH3-20-GO | 20 (40 μL) | 200 μL |  |
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| ALKBH3-20-GR | 20 (40 μL) | 200 μL |  |
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| ALKBH3-20-AQ | 20 (40 μL) | 200 μL |  |
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The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]
Gene Symbol : ALKBH3
Gene Name : AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase
Chromosome : CHR 11: 438,808,06-439,202,74
Locus : 11p11.2
Alt. Genes : RAD50
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