This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ALOX15B-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
ALOX15B-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
ALOX15B-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
ALOX15B-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
ALOX15B-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : ALOX15B
Gene Name : Arachidonate 15-lipoxygenase, type B
Chromosome : CHR 17: 803,903,9-804,913,3
Locus : 17p13.1
Alt. Genes : PRMT3
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