The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALPP-20-RE | 20 (40 μL) | 200 μL |  |
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| ALPP-20-OR | 20 (40 μL) | 200 μL |  |
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| ALPP-20-GO | 20 (40 μL) | 200 μL |  |
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| ALPP-20-GR | 20 (40 μL) | 200 μL |  |
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| ALPP-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]
Gene Symbol : ALPP
Gene Name : Alkaline phosphatase, placental
Chromosome : CHR 2: 232,378,533-232,382,888
Locus : 2q37.1
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