This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AMOT-20-RE | 20 (40 μL) | 200 μL |  |
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| AMOT-20-OR | 20 (40 μL) | 200 μL |  |
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| AMOT-20-GO | 20 (40 μL) | 200 μL |  |
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| AMOT-20-GR | 20 (40 μL) | 200 μL |  |
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| AMOT-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : AMOT
Gene Name : Angiomotin
Chromosome : CHR X: 112,840,945-112,774,876
Locus : Xq23
Alt. Genes : BCAP31
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