This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANAPC7-20-RE | 20 (40 μL) | 200 μL |  |
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| ANAPC7-20-OR | 20 (40 μL) | 200 μL |  |
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| ANAPC7-20-GO | 20 (40 μL) | 200 μL |  |
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| ANAPC7-20-GR | 20 (40 μL) | 200 μL |  |
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| ANAPC7-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Gene Symbol : ANAPC7
Gene Name : Anaphase promoting complex subunit 7
Chromosome : CHR 12: 110,403,729-110,372,899
Locus : 12q24.11
Alt. Genes : HIPK3
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