The protein encoded by this gene belongs to the family of ankyrin repeat-containing proteins, and contains two distinct arrays of ankyrin repeats in its amino-terminal region, one with 15 ankyrin repeats, and the other with 10 ankyrin repeats. It also contains a nuclear export signal, nuclear localization signal, and a cyclin-binding RXL motif. Localization of this protein to the nucleus has been shown experimentally, and interactions between this protein and cyclin-dependent kinase 2 have been observed. It has been suggested that this protein plays a role in both DNA replication and in both anti-viral and anti-bacterial innate immune pathways. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ANKRD17-20-RE | 20 (40 μL) | 200 μL | ![]() |
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ANKRD17-20-OR | 20 (40 μL) | 200 μL | ![]() |
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ANKRD17-20-GO | 20 (40 μL) | 200 μL | ![]() |
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ANKRD17-20-GR | 20 (40 μL) | 200 μL | ![]() |
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ANKRD17-20-AQ | 20 (40 μL) | 200 μL | ![]() |
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The protein encoded by this gene belongs to the family of ankyrin repeat-containing proteins, and contains two distinct arrays of ankyrin repeats in its amino-terminal region, one with 15 ankyrin repeats, and the other with 10 ankyrin repeats. It also contains a nuclear export signal, nuclear localization signal, and a cyclin-binding RXL motif. Localization of this protein to the nucleus has been shown experimentally, and interactions between this protein and cyclin-dependent kinase 2 have been observed. It has been suggested that this protein plays a role in both DNA replication and in both anti-viral and anti-bacterial innate immune pathways. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Symbol : ANKRD17
Gene Name : Ankyrin repeat domain 17
Chromosome : CHR 4: 732,591,41-730,739,65
Locus : 4q13.3
Alt. Genes : RBM12
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