This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANO6-20-RE | 20 (40 μL) | 200 μL |  |
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| ANO6-20-OR | 20 (40 μL) | 200 μL |  |
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| ANO6-20-GO | 20 (40 μL) | 200 μL |  |
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| ANO6-20-GR | 20 (40 μL) | 200 μL |  |
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| ANO6-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Gene Symbol : ANO6
Gene Name : Anoctamin 6
Chromosome : CHR 12: 452,159,86-454,404,03
Locus : 12q12
Alt. Genes : ENAM
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