This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AP1S3-20-RE | 20 (40 μL) | 200 μL |  |
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| AP1S3-20-OR | 20 (40 μL) | 200 μL |  |
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| AP1S3-20-GO | 20 (40 μL) | 200 μL |  |
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| AP1S3-20-GR | 20 (40 μL) | 200 μL |  |
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| AP1S3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Symbol : AP1S3
Gene Name : Adaptor related protein complex 1 sigma 3 subunit
Chromosome : CHR 2: 223,837,601-223,755,329
Locus : 2q36.1
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