Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy. [provided by RefSeq, Feb 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AP3B2-20-RE | 20 (40 μL) | 200 μL |  |
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| AP3B2-20-OR | 20 (40 μL) | 200 μL |  |
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| AP3B2-20-GO | 20 (40 μL) | 200 μL |  |
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| AP3B2-20-GR | 20 (40 μL) | 200 μL |  |
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| AP3B2-20-AQ | 20 (40 μL) | 200 μL |  |
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Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy. [provided by RefSeq, Feb 2017]
Gene Symbol : AP3B2
Gene Name : Adaptor related protein complex 3 beta 2 subunit
Chromosome : CHR 15: 827,101,11-826,592,80
Locus : 15q25.2
Alt. Genes : SGK2
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