This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). [provided by RefSeq, Jan 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AP5Z1-20-RE | 20 (40 μL) | 200 μL |  |
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| AP5Z1-20-OR | 20 (40 μL) | 200 μL |  |
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| AP5Z1-20-GO | 20 (40 μL) | 200 μL |  |
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| AP5Z1-20-GR | 20 (40 μL) | 200 μL |  |
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| AP5Z1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). [provided by RefSeq, Jan 2011]
Gene Symbol : AP5Z1
Gene Name : Adaptor related protein complex 5 zeta 1 subunit
Chromosome : CHR 7: 477,561,6-479,439,4
Locus : 7p22.1
Alt. Genes : RAD50
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