The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| APBA1-20-RE | 20 (40 μL) | 200 μL |  |
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| APBA1-20-OR | 20 (40 μL) | 200 μL |  |
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| APBA1-20-GO | 20 (40 μL) | 200 μL |  |
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| APBA1-20-GR | 20 (40 μL) | 200 μL |  |
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| APBA1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008]
Gene Symbol : APBA1
Gene Name : Amyloid beta precursor protein binding family A member 1
Chromosome : CHR 9: 696,730,11-694,275,31
Locus : 9q21.12
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