The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
APBA2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
APBA2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
APBA2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
APBA2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
APBA2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017]
Gene Symbol : APBA2
Gene Name : Amyloid beta precursor protein binding family A member 2
Chromosome : CHR 15: 288,854,78-291,183,14
Locus : 15q13.1
Alt. Genes : CEBPZ
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