This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| APOBEC3H-20-RE | 20 (40 μL) | 200 μL |  |
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| APOBEC3H-20-OR | 20 (40 μL) | 200 μL |  |
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| APOBEC3H-20-GO | 20 (40 μL) | 200 μL |  |
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| APOBEC3H-20-GR | 20 (40 μL) | 200 μL |  |
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| APOBEC3H-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Gene Symbol : APOBEC3H
Gene Name : Apolipoprotein B mRNA editing enzyme catalytic subunit 3H
Chromosome : CHR 22: 390,972,03-391,040,66
Locus : 22q13.1
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