The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
APPL1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
APPL1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
APPL1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
APPL1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
APPL1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
Gene Symbol : APPL1
Gene Name : Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
Chromosome : CHR 3: 572,277,36-572,734,70
Locus : 3p14.3
Alt. Genes : SGK2
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