This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AQP4-20-RE | 20 (40 μL) | 200 μL |  |
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| AQP4-20-OR | 20 (40 μL) | 200 μL |  |
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| AQP4-20-GO | 20 (40 μL) | 200 μL |  |
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| AQP4-20-GR | 20 (40 μL) | 200 μL |  |
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| AQP4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
Gene Symbol : AQP4
Gene Name : Aquaporin 4
Chromosome : CHR 18: 268,658,43-268,520,37
Locus : 18q11.2
Alt. Genes : DNAL4
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