The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARAP1-20-RE | 20 (40 μL) | 200 μL |  |
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| ARAP1-20-OR | 20 (40 μL) | 200 μL |  |
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| ARAP1-20-GO | 20 (40 μL) | 200 μL |  |
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| ARAP1-20-GR | 20 (40 μL) | 200 μL |  |
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| ARAP1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Gene Symbol : ARAP1
Gene Name : ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Chromosome : CHR 11: 727,523,88-726,850,68
Locus : 11q13.4
Alt. Genes : FEM1B
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