The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARAP2-20-RE | 20 (40 μL) | 200 μL |  |
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| ARAP2-20-OR | 20 (40 μL) | 200 μL |  |
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| ARAP2-20-GO | 20 (40 μL) | 200 μL |  |
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| ARAP2-20-GR | 20 (40 μL) | 200 μL |  |
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| ARAP2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
Gene Symbol : ARAP2
Gene Name : ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Chromosome : CHR 4: 362,448,31-360,051,85
Locus : 4p14
Alt. Genes : ZNF263
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