This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGAP22-20-RE | 20 (40 μL) | 200 μL |  |
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| ARHGAP22-20-OR | 20 (40 μL) | 200 μL |  |
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| ARHGAP22-20-GO | 20 (40 μL) | 200 μL |  |
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| ARHGAP22-20-GR | 20 (40 μL) | 200 μL |  |
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| ARHGAP22-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Symbol : ARHGAP22
Gene Name : Rho GTPase activating protein 22
Chromosome : CHR 10: 486,562,64-484,298,30
Locus : 10q11.22-q11.23
Alt. Genes : OPTN
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