Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ARHGAP26-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGAP26-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGAP26-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGAP26-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGAP26-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
Gene Symbol : ARHGAP26
Gene Name : Rho GTPase activating protein 26
Chromosome : CHR 5: 142,770,369-143,229,006
Locus : 5q31.3
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