This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGAP42-20-RE | 20 (40 μL) | 200 μL |  |
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| ARHGAP42-20-OR | 20 (40 μL) | 200 μL |  |
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| ARHGAP42-20-GO | 20 (40 μL) | 200 μL |  |
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| ARHGAP42-20-GR | 20 (40 μL) | 200 μL |  |
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| ARHGAP42-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]
Gene Symbol : ARHGAP42
Gene Name : Rho GTPase activating protein 42
Chromosome : CHR 11: 100,687,675-100,993,940
Locus : 11q22.1
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