Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGEF11-20-RE | 20 (40 μL) | 200 μL |  |
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| ARHGEF11-20-OR | 20 (40 μL) | 200 μL |  |
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| ARHGEF11-20-GO | 20 (40 μL) | 200 μL |  |
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| ARHGEF11-20-GR | 20 (40 μL) | 200 μL |  |
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| ARHGEF11-20-AQ | 20 (40 μL) | 200 μL |  |
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Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : ARHGEF11
Gene Name : Rho guanine nucleotide exchange factor 11
Chromosome : CHR 1: 157,046,902-156,934,839
Locus : 1q23.1
Alt. Genes : ZNF263
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