Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGEF12-20-RE | 20 (40 μL) | 200 μL |  |
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| ARHGEF12-20-OR | 20 (40 μL) | 200 μL |  |
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| ARHGEF12-20-GO | 20 (40 μL) | 200 μL |  |
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| ARHGEF12-20-GR | 20 (40 μL) | 200 μL |  |
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| ARHGEF12-20-AQ | 20 (40 μL) | 200 μL |  |
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Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Symbol : ARHGEF12
Gene Name : Rho guanine nucleotide exchange factor 12
Chromosome : CHR 11: 120,336,275-120,489,935
Locus : 11q23.3
Alt. Genes : FEM1B
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