Rho GTPases alternate between an inactive GDP-bound state and an active GTP-bound state, and GEFs facilitate GDP/GTP exchange. This gene encodes a guanine nucleotide exchange factor (GEF) which interacts with Rho GTPases involved in contraction of vascular smooth muscles, regulation of responses to angiotensin II and lens cell differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGEF25-20-RE | 20 (40 μL) | 200 μL |  |
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| ARHGEF25-20-OR | 20 (40 μL) | 200 μL |  |
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| ARHGEF25-20-GO | 20 (40 μL) | 200 μL |  |
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| ARHGEF25-20-GR | 20 (40 μL) | 200 μL |  |
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| ARHGEF25-20-AQ | 20 (40 μL) | 200 μL |  |
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Rho GTPases alternate between an inactive GDP-bound state and an active GTP-bound state, and GEFs facilitate GDP/GTP exchange. This gene encodes a guanine nucleotide exchange factor (GEF) which interacts with Rho GTPases involved in contraction of vascular smooth muscles, regulation of responses to angiotensin II and lens cell differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Symbol : ARHGEF25
Gene Name : Rho guanine nucleotide exchange factor 25
Chromosome : CHR 12: 576,101,79-576,172,44
Locus : 12q13.3
Alt. Genes : SUGP2
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