This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ARHGEF26-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGEF26-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGEF26-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGEF26-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGEF26-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Gene Symbol : ARHGEF26
Gene Name : Rho guanine nucleotide exchange factor 26
Chromosome : CHR 3: 154,121,002-154,257,826
Locus : 3q25.2
Alt. Genes : LRPPRC
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