Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ARHGEF6-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGEF6-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGEF6-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGEF6-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
ARHGEF6-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability. [provided by RefSeq, Jul 2008]
Gene Symbol : ARHGEF6
Gene Name : Rac/Cdc42 guanine nucleotide exchange factor 6
Chromosome : CHR X: 136,781,655-136,665,546
Locus : Xq26.3
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