This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARMC10-20-RE | 20 (40 μL) | 200 μL |  |
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| ARMC10-20-OR | 20 (40 μL) | 200 μL |  |
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| ARMC10-20-GO | 20 (40 μL) | 200 μL |  |
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| ARMC10-20-GR | 20 (40 μL) | 200 μL |  |
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| ARMC10-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]
Gene Symbol : ARMC10
Gene Name : Armadillo repeat containing 10
Chromosome : CHR 7: 103,074,726-103,099,762
Locus : 7q22.1
Alt. Genes : PREB
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