Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ASAH2-20-RE | 20 (40 μL) | 200 μL |  |
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| ASAH2-20-OR | 20 (40 μL) | 200 μL |  |
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| ASAH2-20-GO | 20 (40 μL) | 200 μL |  |
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| ASAH2-20-GR | 20 (40 μL) | 200 μL |  |
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| ASAH2-20-AQ | 20 (40 μL) | 200 μL |  |
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Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008]
Gene Symbol : ASAH2
Gene Name : N-acylsphingosine amidohydrolase 2
Chromosome : CHR 10: 502,515,63-501,848,60
Locus : 10q11.23
Alt. Genes : RBM12
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