This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ASB2-20-RE | 20 (40 μL) | 200 μL |  |
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| ASB2-20-OR | 20 (40 μL) | 200 μL |  |
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| ASB2-20-GO | 20 (40 μL) | 200 μL |  |
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| ASB2-20-GR | 20 (40 μL) | 200 μL |  |
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| ASB2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Symbol : ASB2
Gene Name : Ankyrin repeat and SOCS box containing 2
Chromosome : CHR 14: 939,767,95-939,341,52
Locus : 14q32.12
Alt. Genes : ZNF263
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