The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ASB7-20-RE | 20 (40 μL) | 200 μL |  |
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| ASB7-20-OR | 20 (40 μL) | 200 μL |  |
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| ASB7-20-GO | 20 (40 μL) | 200 μL |  |
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| ASB7-20-GR | 20 (40 μL) | 200 μL |  |
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| ASB7-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : ASB7
Gene Name : Ankyrin repeat and SOCS box containing 7
Chromosome : CHR 15: 100,602,549-100,651,700
Locus : 15q26.3
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