This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ASIC3-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ASIC3-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ASIC3-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ASIC3-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| ASIC3-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
Gene Symbol : ASIC3
Gene Name : Acid sensing ion channel subunit 3
Chromosome : CHR 7: 151,048,291-151,052,755
Locus : 7q36.1
Alt. Genes : ABI2
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.