This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ASIC4-20-RE | 20 (40 μL) | 200 μL |  |
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| ASIC4-20-OR | 20 (40 μL) | 200 μL |  |
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| ASIC4-20-GO | 20 (40 μL) | 200 μL |  |
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| ASIC4-20-GR | 20 (40 μL) | 200 μL |  |
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| ASIC4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]
Gene Symbol : ASIC4
Gene Name : Acid sensing ion channel subunit family member 4
Chromosome : CHR 2: 219,514,169-219,538,771
Locus : 2q35
Alt. Genes : ARL4C
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