Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATG10-20-RE | 20 (40 μL) | 200 μL |  |
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| ATG10-20-OR | 20 (40 μL) | 200 μL |  |
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| ATG10-20-GO | 20 (40 μL) | 200 μL |  |
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| ATG10-20-GR | 20 (40 μL) | 200 μL |  |
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| ATG10-20-AQ | 20 (40 μL) | 200 μL |  |
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Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]
Gene Symbol : ATG10
Gene Name : Autophagy related 10
Chromosome : CHR 5: 819,720,20-822,585,01
Locus : 5q14.1-q14.2
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