The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ATP1A3-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
ATP1A3-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
ATP1A3-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
ATP1A3-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
ATP1A3-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Symbol : ATP1A3
Gene Name : ATPase Na+/K+ transporting subunit alpha 3
Chromosome : CHR 19: 419,942,75-419,665,81
Locus : 19q13.2
Alt. Genes : SUGP2
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