The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ATP23-20-RE | 20 (40 μL) | 200 μL | ![]() |
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ATP23-20-OR | 20 (40 μL) | 200 μL | ![]() |
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ATP23-20-GO | 20 (40 μL) | 200 μL | ![]() |
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ATP23-20-GR | 20 (40 μL) | 200 μL | ![]() |
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ATP23-20-AQ | 20 (40 μL) | 200 μL | ![]() |
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The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Gene Symbol : ATP23
Gene Name : ATP23 metallopeptidase and ATP synthase assembly factor homolog
Chromosome : CHR 12: 579,415,03-579,572,68
Locus : 12q14.1
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